Triple therapy versus dual or monotherapy with long-acting bronchodilators for chronic obstructive pulmonary disease. A systematic review and meta-analysis

MJ Mammen, DR Lloyd, S Kumar… - Annals of the …, 2020 - atsjournals.org
… therapy compared with long-acting β-agonist/long-acting muscarinic antagonist … long-acting
bronchodilator in patients with stable COPD who complained of dyspnea and/or exercise

A reappraisal of inspiratory capacity in chronic obstructive pulmonary disease: clinical correlates and role of long-acting muscarinic antagonists and long-acting β2 …

F Danzo, D Radovanovic, M Gatti, M Saad… - Expert Review of …, 2022 - Taylor & Francis
… with improvements in dyspnea and exercise performance. We … that TLC is almost constant
when corrected for age, there is a … bronchodilator in patients with COPD improved the IC and …

The effect of long-acting dual bronchodilator therapy on exercise tolerance, dynamic hyperinflation, and dead space during constant work rate exercise in COPD

WW Stringer, J Porszasz, M Cao… - Journal of Applied …, 2021 - journals.physiology.org
increase exercise tolerance during high intensity, constant work rate, cycle ergometer exercise
in stable COPD patientsbronchodilator therapies in COPD: a network meta-analysis. Int J …

Pharmacologic therapies in patients with exacerbation of chronic obstructive pulmonary disease: a systematic review with meta-analysis

CC Dobler, AS Morrow, B Beuschel… - Annals of internal …, 2020 - acpjournals.org
Long-acting bronchodilators and inhaled corticosteroids (… We also examined functional
capacity (timed walking tests and … –Sidik–Jonkman variance correction was used as a sensitivity …

Pharmacotherapy and lung function decline in patients with chronic obstructive pulmonary disease. A systematic review

BR Celli, JA Anderson, NJ Cowans, C Crim… - American journal of …, 2021 - atsjournals.org
… of patients, included different long-acting pharmacological … long-acting bronchodilators
(LABDs), either long-acting muscarinic antagonist or long-acting beta adrenergic bronchodilators

Small airways response to bronchodilators in adults with asthma or COPD: a systematic review

MA Almeshari, NY Alobaidi, E Sapey… - … journal of chronic …, 2021 - Taylor & Francis
… dyspnea and increased exercise performance. Citation23,… In this study, short-acting
bronchodilators, long-acting beta2 … included studies have reported this correction. The need to …

Dual bronchodilation for the treatment of COPD: from bench to bedside

M Cazzola, C Page, P Rogliani… - British Journal of …, 2022 - Wiley Online Library
… many patients who are receiving long-acting bronchodilators … therapy is to improve exercise
capacity in COPD patients, dual … This meta-analysis also suggested a greater ability of dual …

Dual LABA/LAMA therapy versus LABA or LAMA monotherapy for chronic obstructive pulmonary disease. A systematic review and meta-analysis in support of the …

MJ Mammen, V Pai, SD Aaron, L Nici… - Annals of the …, 2020 - atsjournals.org
… , out-of-pocket costs for patients, and exercise capacity were ranked as important outcomes.
… , dual long-acting bronchodilator therapy is more expensive than long-acting bronchodilator

Comparative efficacy of umeclidinium/vilanterol versus other bronchodilators for the treatment of chronic obstructive pulmonary disease: a network meta-analysis

AS Ismaila, K Haeussler, A Czira, V Tongbram… - Advances in …, 2022 - Springer
… This systematic literature review and network meta-analysis (NMA) … Long-acting bronchodilators
are the mainstay of … relevant to patients with COPD, such as exercise capacity, because …

Comparative efficacy of single-inhaler triple therapies for COPD: A protocol for systematic review and network meta-analysis

Y Jiang, H Hu, S Leung - Plos one, 2021 - journals.plos.org
… and exercise toleranceCOPD patients with persistent symptoms or history of exacerbations
should be treated with combined long-acting muscarinic antagonists (LAMA) and long-acting